Genetic Mutations Identified in Unicentric Castleman Disease!

Recent research from physicians in the CDCN network has uncovered a gene that is mutated in the lymph node cells of some UCD patients!  A team of researchers, including Dr. Ken Young, a Professor of Hematopath… READ MORE

Clinical Trial for Sirolimus in iMCD Launching this Summer!

  The first US clinical trial for a Castleman disease treatment in 8 years launches in Summer 2019! Co-Founders of the CDCN, Dr. David Fajgenbaum at the University of Pennsylvania and Dr. Frits va… READ MORE

Chan Zuckerberg Initiative Partnering with CDCN to Accelerate CD Research and Revolutionize Rare Disease Research

The Castleman Disease Collaborative Network (CDCN) is excited to announce that we're partnering with the Chan Zuckerberg Initiative (CZI) to accelerate Castleman disease research and revolutionize rare disea… READ MORE

First CD Genome Project Data Publicly Available!

   Thanks to a study funded by the CDCN's Castleman Disease Warriors, the Wharton Class of 2015, and the Penn Orphan Disease Center, the first whole genome sequencing of Castleman patients was carried out b… READ MORE

CDCN Publishes on the Collaborative Network Approach!

When the CDCN was founded in 2012 with the goal of curing Castleman disease, the failure of the traditional research approach to Castleman disease was evident: there were few published studies, limited s… READ MORE

2018 CDCN Highlights!

2018 has been an amazing year for the CDCN! In honor of all the progress that we have recently made thanks to support of hundreds of patients, loved ones, and community members from around the world, we wanted to high… READ MORE

Fourth Annual Quest for a Cure!

The Fourth Annual Quest for a Cure Gala was an incredible success! Quest for a Cure was held on November 16, 2018 at the beautiful Arts Ballroom in Philadelphia, PA. Our CDCN community of patients, loved ones, an… READ MORE

CDCN Research Identifies Lab Tests Predictive of Siltuximab Response in iMCD

The Castleman Disease Collaborative Network (CDCN) is excited to announce the recent publication of a study that identified key laboratory markers that help to predict whether patients with idiopathic multicentric Cas… READ MORE

CDCN at the 2018 ASH Conference!

The Castleman Disease Collaborative Network had its best showing yet at the American Society of Hematology’s Annual Meeting and Exposition, the premier event of the global hematology community! This year, A… READ MORE

Fifth Annual Patient & Loved One Summit

The 2018 Patient and Loved One Summit was a hit! The fifth annual summit took place on September 21-22, 2018 at the University of Pennsylvania and brought together over 90 patients, loved ones, and CDCN volunte… READ MORE