ACCELERATE REGISTRY – Now registering patients!

First ever natural history registry for Castleman disease patients around the world! This registry will track what treatments have been used in Castleman disease patients and how well these treatments work in different types of people.  This study also looks at how Castleman Disease starts and progresses over time in patients. In this study, the CDCN will collect clinical data from Castleman disease patients around the world. Register or find out more information here!


CASTLEBANK – Now collecting samples!

Studying Castleman disease is difficult because it is difficult to get samples of blood, saliva, and frozen lymph nodes for research. Samples may be stored in various places all over the world with no way of other researchers being able to obtain them. In order to find out what causes Castleman disease, researchers need access to these samples so they can study them. The CastleBank will provide a central location for all samples. Researchers studying Castleman disease will then have access to these samples, making it much easier to study the disease! Find out more information or sign-up to donate samples here!


WHOLE EXOME SEQUENCING - In need of funding!

Mutations, or defects, in a gene may cause the gene to no longer function correctly. For example, a mutation in a gene that controls the immune system could cause the immune system to become uncontrollable. These gene mutations may be passed along in families from generation to generation. Sequencing exomes, the coding region of the genome, will help us find out if there is a common change in an inflammatory gene among patients with Castleman Disease and will help us know if this is a genetic disease. It will also investigate the role of a key immune cell called a T-cell. Whole exome sequencing of one patient costs about $1,150 per patient. To fund a portion or whole exome sequencing of one or more patients, please donate here

 

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