HHV-8-negative/"idiopathic" multicentric Castleman disease Diagnostic Calculator

Please click the features below to determine if you or your patient meets the diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman (iMCD) disease based on the international, evidence-based consensus diagnostic criteria published in 2017. To read the full diagnostic criteria, click here.


Exclusionary Criteria: For the rest of the checkboxes below, please select any diseases that were diagnosed at the same time as Castleman disease to determine if they are exclusionary criteria based on the 2017 diagnostic criteria for iMCD. If any of these diseases were diagnosed prior to Castleman disease, please do NOT select the following exclusionary diagnoses.

The idiopathic multicentric Castleman disease diagnostic calculator is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information should not be used as a substitute for professional diagnosis and treatment. Please consult your health care provider and/or contact the CDCN (info@castlemannetwork.org) with questions regarding diagnosis. The CDCN expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site.